Applying solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits incorporate:

You frequently get involved in conversations about science and faith. You may have also composed many books on the topic. Don’t you believe that in some unspecified time in the future We'll know everything Which God’s role might be more than?

Back in 1991, Sumio Iijima in the NEC Corporation had noted the synthesis of carbon nanotubes. Band structure calculations suggested that these nanotubes could exhibit metallic band conduction. This would be a significant advantage more than the conducting polymers we had explored, which were, actually, disordered semiconductors providing merely variable-variety hopping conductivity.

Our perform was speedily followed up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors made from one- and multi-walled carbon nanotubes in Used Physics Letters.

That could be a aspiration of mine and we established to operate with a scrumptious dose of naivety. This can be something which will probably yield breathtaking leads to the for a longer time expression, but that does not issue. You should not only want to work around the queries of tomorrow, but additionally within the queries in the day following tomorrow.’

Our investigate ranges through the biophysics of DNA to synthetic cells and further than. Remember to have a look underneath on the spectrum of our present jobs.

We use nanofabricated microfluidic buildings to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this assess the basic position of spatial confinement on the molecular and cellular level. Our initiatives contain the next:

Instance (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in purple, ceesdekker.net along with a 3D rendering of your motion with the DNA rod is displayed.

What if, in place of making use of conventional top rated-down silicon electronics, transistors might be crafted from the bottom up applying solitary natural and organic molecules since the switching factors? This concept, which grew to become The premise of these days’s subject of molecular electronics, very first emerged during the 1970s.

There was one particular trouble nevertheless — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being actually not this kind of excellent conductors, which was relatively disappointing. We Consequently broadened our watch to test to uncover extra promising molecules.

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division

2006, first demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in reliable-point out nanopores; and initial estimate of electrokinetic Strength conversion inside of a nanofluidic channel

Developments in nanotechnology during the nineties manufactured making Digital products from solitary molecules a likelihood. Cees Dekker recounts how his crew designed a place-temperature transistor based upon one carbon nanotube.

Illustration (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, and also a 3D rendering in the movement in the DNA rod is exhibited.